Mitogen-Activated Protein Kinase Phosphatase-1 Deficiency Decreases Atherosclerosis in Apolipoprotein E Null Mice by Reducing Monocyte Chemoattractant Protein-1 Levels

RATIONALE: We previously reported that mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is necessary for oxidized phospholipids to induce monocyte chemoattractant protein-1 (MCP-1) secretion by human aortic endothelial cells. We also reported that inhibition of tyrosine phosphatases...

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Main Authors: Imaizumi, Satoshi, Grijalva, Victor, Priceman, Saul, Wu, Lily, Su, Feng, Farias-Eisner, Robin, Hama, Susan, Navab, Mohamad, Fogelman, Alan M., Reddy, Srinivasa T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037189/
https://ncbi.nlm.nih.gov/pubmed/20619710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2010.05.009
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