Apolipoprotein A-I Mimetic Peptides Inhibit Expression and Activity of Hypoxia-Inducible Factor-1α in Human Ovarian Cancer Cell Lines and a Mouse Ovarian Cancer Model

Our previous results demonstrated that the apolipoprotein A-I (apoA-I) mimetic peptides L-4F and L-5F inhibit vascular endothelial growth factor production and tumor angiogenesis. The present study was designed to test whether apoA-I mimetic peptides inhibit the expression and activity of hypoxia-in...

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Autori principali: Gao, Feng, Chattopadhyay, Arnab, Navab, Mohamad, Grijalva, Victor, Su, Feng, Fogelman, Alan M., Reddy, Srinivasa T., Farias-Eisner, Robin
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2012
Soggetti:
Drug Discovery and Translational Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400800/
https://ncbi.nlm.nih.gov/pubmed/22537771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.191544
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