A Novel Anti-Atherogenic Role for COX-2 - Potential Mechanism for the Cardiovascular Side Effects of COX-2 Inhibitors

Atherosclerosis, the underlying cause of cardiovascular disease, is characterized by lipid accumulation, lipoprotein oxidation, and inflammation. Products of the cyclooxygenase (COX) pathway participate in acute and chronic inflammation. The inducible form of COX, COX-2, generates lipid mediators of...

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Hlavní autoři: Narasimha, Ajay, Watanabe, Junji, Lin, James, Hama, Susan, Langenbach, Robert, Navab, Mohamad, Fogelman, Alan M., Reddy, Srinivasa T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701232/
https://ncbi.nlm.nih.gov/pubmed/17643885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2007.03.004
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