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ApoE(−/−) Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function

OBJECTIVE: We previously reported that Hemopexin (Hx), a heme scavenger, is significantly increased and associated with proinflammatory HDL under atherogenic conditions. Although it is established that Hx together with macrophages plays a role in mitigating oxidative damage, the role of Hx in the de...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Mehta, Niyati U., Grijalva, Victor, Hama, Susan, Wagner, Alan, Navab, Mohamad, Fogelman, Alan M., Reddy, Srinivasa T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882257/
https://ncbi.nlm.nih.gov/pubmed/27079878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306991
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