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Intestine may be a major site of action for the apoA-I mimetic peptide 4F whether administered subcutaneously or orally
To determine if the dose of peptide administered or the plasma level was more important, doses of 0.15, 0.45, 4.5, or 45 mg/kg/day of the peptide D-4F were administered orally or subcutaneously (SQ) to apoliptotein (apo)E null mice. Plasma levels of peptide were ∼1,000-fold higher when administered...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3090241/ https://ncbi.nlm.nih.gov/pubmed/21444758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M013144 |
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