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Intestine may be a major site of action for the apoA-I mimetic peptide 4F whether administered subcutaneously or orally

To determine if the dose of peptide administered or the plasma level was more important, doses of 0.15, 0.45, 4.5, or 45 mg/kg/day of the peptide D-4F were administered orally or subcutaneously (SQ) to apoliptotein (apo)E null mice. Plasma levels of peptide were ∼1,000-fold higher when administered...

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Bibliografiset tiedot
Päätekijät: Navab, Mohamad, Reddy, Srinivasa T., Anantharamaiah, G. M., Imaizumi, Satoshi, Hough, Greg, Hama, Susan, Fogelman, Alan M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090241/
https://ncbi.nlm.nih.gov/pubmed/21444758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M013144
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