A Novel Anti-Atherogenic Role for COX-2 - Potential Mechanism for the Cardiovascular Side Effects of COX-2 Inhibitors

Atherosclerosis, the underlying cause of cardiovascular disease, is characterized by lipid accumulation, lipoprotein oxidation, and inflammation. Products of the cyclooxygenase (COX) pathway participate in acute and chronic inflammation. The inducible form of COX, COX-2, generates lipid mediators of...

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Main Authors: Narasimha, Ajay, Watanabe, Junji, Lin, James, Hama, Susan, Langenbach, Robert, Navab, Mohamad, Fogelman, Alan M., Reddy, Srinivasa T.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701232/
https://ncbi.nlm.nih.gov/pubmed/17643885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2007.03.004
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