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Tumor formation in a mouse model of colitis-associated colon cancer does not require COX-1 or COX-2 expression
Cyclooxygenase-2 (COX-2), a key enzyme of prostanoid biosynthesis, plays an important role in both hereditary and spontaneous colon cancer. Individuals with ulcerative colitis are also at high risk for colorectal cancer. To investigate the role of Cox-2 in colitis-associated colon cancer, we subject...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847091/ https://ncbi.nlm.nih.gov/pubmed/20061361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq002 |
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