Replication Timing of Human Telomeres Is Chromosome Arm–Specific, Influenced by Subtelomeric Structures and Connected to Nuclear Localization

The mechanisms governing telomere replication in humans are still poorly understood. To fill this gap, we investigated the timing of replication of single telomeres in human cells. Using in situ hybridization techniques, we have found that specific telomeres have preferential time windows for replic...

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書誌詳細
主要な著者: Arnoult, Nausica, Schluth-Bolard, Caroline, Letessier, Anne, Drascovic, Irena, Bouarich-Bourimi, Rachida, Campisi, Judith, Kim, Sahn-ho, Boussouar, Amina, Ottaviani, Alexandre, Magdinier, Frédérique, Gilson, Eric, Londoño-Vallejo, Arturo
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2010
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858680/
https://ncbi.nlm.nih.gov/pubmed/20421929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000920
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