Identification of a perinuclear positioning element in human subtelomeres that requires A-type lamins and CTCF

The localization of genes within the nuclear space is of paramount importance for proper genome functions. However, very little is known on the cis-acting elements determining subnuclear positioning of chromosome segments. We show here that the D4Z4 human subtelomeric repeat localizes a telomere at...

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Main Authors: Ottaviani, Alexandre, Schluth-Bolard, Caroline, Rival-Gervier, Sylvie, Boussouar, Amina, Rondier, Delphine, Foerster, Andrea M, Morere, Julia, Bauwens, Serge, Gazzo, Sophie, Callet-Bauchu, Evelyne, Gilson, Eric, Magdinier, Frédérique
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735173/
https://ncbi.nlm.nih.gov/pubmed/19644448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.201
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