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Replication Timing of Human Telomeres Is Chromosome Arm–Specific, Influenced by Subtelomeric Structures and Connected to Nuclear Localization

The mechanisms governing telomere replication in humans are still poorly understood. To fill this gap, we investigated the timing of replication of single telomeres in human cells. Using in situ hybridization techniques, we have found that specific telomeres have preferential time windows for replic...

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Detalhes bibliográficos
Main Authors: Arnoult, Nausica, Schluth-Bolard, Caroline, Letessier, Anne, Drascovic, Irena, Bouarich-Bourimi, Rachida, Campisi, Judith, Kim, Sahn-ho, Boussouar, Amina, Ottaviani, Alexandre, Magdinier, Frédérique, Gilson, Eric, Londoño-Vallejo, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858680/
https://ncbi.nlm.nih.gov/pubmed/20421929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000920
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