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D4Z4 as a prototype of CTCF and lamins-dependent insulator in human cells

Using cellular models that mimic the organizations of the subtelomeric 4q35 locus found in patients affected with Facio-Scapulo-Humeral Dystrophy (FSHD) and in healthy individuals, we recently investigated the biological function of the D4Z4 macrosatellite in this subtelomeric context. We demonstrat...

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Hlavní autoři: Ottaviani, Alexandre, Schluth-Bolard, Caroline, Gilson, Eric, Magdinier, Frédérique
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3035130/
https://ncbi.nlm.nih.gov/pubmed/21327102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.1.1.10799
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