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On the Value of Intra-Motif Dependencies of Human Insulator Protein CTCF

The binding affinity of DNA-binding proteins such as transcription factors is mainly determined by the base composition of the corresponding binding site on the DNA strand. Most proteins do not bind only a single sequence, but rather a set of sequences, which may be modeled by a sequence motif. Algo...

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Autors principals: Eggeling, Ralf, Gohr, André, Keilwagen, Jens, Mohr, Michaela, Posch, Stefan, Smith, Andrew D., Grosse, Ivo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3899044/
https://ncbi.nlm.nih.gov/pubmed/24465627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085629
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