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Combining phylogenetic footprinting with motif models incorporating intra-motif dependencies

BACKGROUND: Transcriptional gene regulation is a fundamental process in nature, and the experimental and computational investigation of DNA binding motifs and their binding sites is a prerequisite for elucidating this process. Approaches for de-novo motif discovery can be subdivided in phylogenetic...

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Publicat a:BMC Bioinformatics
Autors principals: Nettling, Martin, Treutler, Hendrik, Cerquides, Jesus, Grosse, Ivo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333389/
https://ncbi.nlm.nih.gov/pubmed/28249564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1495-1
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