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Combined Inactivation of pRB and Hippo Pathways Induces Dedifferentiation in the Drosophila Retina

Functional inactivation of the Retinoblastoma (pRB) pathway is an early and obligatory event in tumorigenesis. The importance of pRB is usually explained by its ability to promote cell cycle exit. Here, we demonstrate that, independently of cell cycle exit control, in cooperation with the Hippo tumo...

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Detaylı Bibliyografya
Asıl Yazarlar: Nicolay, Brandon N., Bayarmagnai, Battuya, Moon, Nam Sung, Benevolenskaya, Elizaveta V., Frolov, Maxim V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858677/
https://ncbi.nlm.nih.gov/pubmed/20421993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000918
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