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The multiple connections between pRB and cell metabolism

The pRB tumor suppressor is traditionally seen as an important regulator of the cell cycle. pRB represses the transcriptional activation of a diverse set of genes by the E2F transcription factors and prevents inappropriate S-phase entry. Advances in our understanding of pRB have documented roles tha...

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Autors principals: Nicolay, Brandon N., Dyson, Nicholas J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836918/
https://ncbi.nlm.nih.gov/pubmed/23916769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2013.07.012
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