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Epigenetic Targeting of Transforming Growth Factor β Receptor II and Implications for Cancer Therapy
The transforming growth factor (TGF) β signaling pathway is involved in many cellular processes including proliferation, differentiation, adhesion, motility and apoptosis. The loss of TGFβ signaling occurs early in carcinogenesis and its loss contributes to tumor progression. The loss of TGFβ respon...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857646/ https://ncbi.nlm.nih.gov/pubmed/20414468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4255/mcpharmacol.09.07 |
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