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Targeting transforming growth factor-β signaling

PURPOSE OF REVIEW: Most cancers are characterized by excessive transforming growth factor-β production by tumors, which can promote tumor growth and mediate epithelial-to-mesenchymal transition. Transforming growth factor-β also has the ability to overproduce extracellular matrix components in respo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pennison, Michael, Pasche, Boris
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640227/
https://ncbi.nlm.nih.gov/pubmed/17906455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCO.0b013e3282f0ad0e
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