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Targeting Transforming Growth Factor-β signaling in liver metastasis of colon cancer

Despite a primary tumor-suppressor role, there is compelling evidence suggesting that TGF-β can promote tumor growth, invasion and metastasis in advanced stages of colorectal cancer. Blocking these tumor-promoting effects of TGF-β provides a potentially important therapeutic strategy for the treatme...

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Bibliographic Details
Main Authors: Zhang, Bixiang, Halder, Sunil K., Zhang, Sanguo, Datta, Pran K.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776056/
https://ncbi.nlm.nih.gov/pubmed/19147275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.11.035
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