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Transforming growth factor-ß as a therapeutic target in systemic sclerosis
Transforming growth factor-ß (TGF-ß) is a pleiotropic cytokine with vital homeostatic functions. Aberrant TGF-ß expression or activity is implicated in the pathogenesis of fibrosis in patients with systemic sclerosis (SSc), thus TGF-ß represents a molecular therapeutic target. Multiple strategies ar...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959159/ https://ncbi.nlm.nih.gov/pubmed/19337284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2009.26 |
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