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Epigenetic Targeting of Transforming Growth Factor β Receptor II and Implications for Cancer Therapy

The transforming growth factor (TGF) β signaling pathway is involved in many cellular processes including proliferation, differentiation, adhesion, motility and apoptosis. The loss of TGFβ signaling occurs early in carcinogenesis and its loss contributes to tumor progression. The loss of TGFβ respon...

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Detalhes bibliográficos
Main Authors: Chowdhury, Sanjib, Ammanamanchi, Sudhakar, Howell, Gillian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857646/
https://ncbi.nlm.nih.gov/pubmed/20414468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4255/mcpharmacol.09.07
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