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Covalent Cross-Linking of Glutathione and Carnosine to Proteins by 4-Oxo-2-nonenal
The lipid oxidation product 4-oxo-2-nonenal (ONE) derived from peroxidation of polyunsaturated fatty acids is a highly reactive protein cross-linking reagent. The major family of cross-links reflects conjugate addition of side-chain nucleophiles such as sulfhydryl or imidazole groups to the C=C of O...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857574/ https://ncbi.nlm.nih.gov/pubmed/19480392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx9000144 |
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