THE ESSENTIAL ROLE OF ERK IN 4-OXO-2-NONENAL MEDIATED CYTOTOXICITY IN SH-SY5Y HUMAN NEUROBLASTOMA CELLS

Previous studies suggest that lipid peroxidation byproducts, such as 4-hydroxynonenal (HNE) and 4-oxo-2-nonenal (ONE), induces cell death in a wide variety of cell types, partly by modulating intracellular signaling pathways. However, the specific mechanisms involved, particularly for ONE, are uncle...

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Autori principali: Lee, Hyun-Pil, Zhu, Xiaochun, Zhu, Xiongwei, Perry, George, Sayre, Lawrence M., Smith, Mark A., Lee, Hyoung-gon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677392/
https://ncbi.nlm.nih.gov/pubmed/19183271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.05883.x
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