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DELIVERY OF THERAPEUTIC PROTEINS

The safety and efficacy of protein therapeutics are limited by three interrelated pharmaceutical issues, in vitro and in vivo instability, immunogenicity and shorter half-lives. Novel drug modifications for overcoming these issues are under investigation and include covalent attachment of poly(ethyl...

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Autors principals: Pisal, Dipak S., Kosloski, Matthew P., Balu-Iyer, Sathy V.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857543/
https://ncbi.nlm.nih.gov/pubmed/20049941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.22054
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