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Immunogenicity Challenges Associated with Subcutaneous Delivery of Therapeutic Proteins

The subcutaneous route of administration has provided convenient and non-inferior delivery of therapeutic proteins compared to intravenous infusion, but there is potential for enhanced immunogenicity toward subcutaneously administered proteins in a subset of patients. Unwanted anti-drug antibody res...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BioDrugs
Hauptverfasser: Jarvi, Nicole L., Balu-Iyer, Sathy V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848667/
https://ncbi.nlm.nih.gov/pubmed/33523413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40259-020-00465-4
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