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Immunogenicity of Subcutaneously Administered Therapeutic Proteins—a Mechanistic Perspective

The administration of therapeutic proteins via the subcutaneous route (sc) is desired for compliance and convenience, but could be challenging due to perceived immunogenic potential or unwanted immune responses. There are clinical and preclinical data supporting as well as refuting the generalized n...

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Detalhes bibliográficos
Main Authors: Fathallah, Anas M., Bankert, Richard B., Balu-Iyer, Sathy V.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787214/
https://ncbi.nlm.nih.gov/pubmed/23856740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9510-6
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