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Immunogenicity of Subcutaneously Administered Therapeutic Proteins—a Mechanistic Perspective

The administration of therapeutic proteins via the subcutaneous route (sc) is desired for compliance and convenience, but could be challenging due to perceived immunogenic potential or unwanted immune responses. There are clinical and preclinical data supporting as well as refuting the generalized n...

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Detalles Bibliográficos
Autores principales: Fathallah, Anas M., Bankert, Richard B., Balu-Iyer, Sathy V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787214/
https://ncbi.nlm.nih.gov/pubmed/23856740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9510-6
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