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DELIVERY OF THERAPEUTIC PROTEINS
The safety and efficacy of protein therapeutics are limited by three interrelated pharmaceutical issues, in vitro and in vivo instability, immunogenicity and shorter half-lives. Novel drug modifications for overcoming these issues are under investigation and include covalent attachment of poly(ethyl...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857543/ https://ncbi.nlm.nih.gov/pubmed/20049941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.22054 |
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