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Dissecting the binding mechanism of the linker histone in live cells: an integrated FRAP analysis

The linker histone H1 has a fundamental role in DNA compaction. Although models for H1 binding generally involve the H1 C-terminal tail and sites S1 and S2 within the H1 globular domain, there is debate about the importance of these binding regions and almost nothing is known about how they work tog...

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Detalhes bibliográficos
Main Authors: Stasevich, Timothy J, Mueller, Florian, Brown, David T, McNally, James G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857466/
https://ncbi.nlm.nih.gov/pubmed/20224551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.24
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