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FRAP and kinetic modeling in the analysis of nuclear protein dynamics: what do we really know?

The binding of nuclear proteins to chromatin in live cells has been analyzed by kinetic modeling procedures applied to experimental data from fluorescence recovery after photobleaching (FRAP). The kinetic models have yielded a number of important biological predictions about transcription, but conce...

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Autors principals: Mueller, Florian, Mazza, Davide, Stasevich, Timothy J., McNally, James G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916960/
https://ncbi.nlm.nih.gov/pubmed/20413286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2010.03.002
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