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Unravelling the mechanism of dual-specificity GAPs

The molecular mechanism by which dual-specificity RasGAPs of the Gap1 subfamily activate the GTP hydrolysis of both Rap and Ras is an unresolved phenomenon. RasGAPs and RapGAPs use different strategies to stimulate the GTPase reaction of their cognate G-proteins. RasGAPs contribute an arginine finge...

詳細記述

保存先:
書誌詳細
主要な著者: Sot, Begoña, Kötting, Carsten, Deaconescu, Delia, Suveyzdis, Yan, Gerwert, Klaus, Wittinghofer, Alfred
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857463/
https://ncbi.nlm.nih.gov/pubmed/20186121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.20
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