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CtIP-BRCA1 modulates the choice of DNA double-strand break repair pathway throughout the cell cycle

The repair of DNA double-strand breaks (DSB) is tightly regulated during the cell cycle. In G1 phase, the absence of a sister chromatid means that repair of DSB occurs through non-homologous end-joining (NHEJ) or microhomology-mediated end-joining (MMEJ)1. These pathways often involve loss of DNA se...

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Библиографические подробности
Главные авторы: Yun, Maximina H., Hiom, Kevin
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857324/
https://ncbi.nlm.nih.gov/pubmed/19357644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07955
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