SENP3-mediated De-conjugation of SUMO2/3 from Promyelocytic Leukemia Is Correlated with Accelerated Cell Proliferation under Mild Oxidative Stress

Small ubiquitin-like modifier (SUMO) 2/3 is known to conjugate to substrates in response to a variety of cellular stresses. However, whether and how SUMO2/3-specific proteases are involved in de-conjugation under cell stress is unclear. Here, we show that low doses of hydrogen peroxide (H(2)O(2)) in...

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Hlavní autoři: Han, Yan, Huang, Chao, Sun, Xuxu, Xiang, Binggang, Wang, Ming, Yeh, Edward T. H., Chen, Yuying, Li, Hui, Shi, Guiying, Cang, Hui, Sun, Yueping, Wang, Jian, Wang, Wei, Gao, Fei, Yi, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857110/
https://ncbi.nlm.nih.gov/pubmed/20181954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.071431
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