Quantitative high-throughput screening identifies cytoprotective molecules that enhance SUMO conjugation via the inhibition of SUMO-specific protease (SENP)2

The development of novel neuroprotective treatments for acute stroke has been fraught with failures, which supports the view of ischemic brain damage as a highly complex multifactorial process. Post-translational modifications such as small ubiquitin-like modifier (SUMO)ylation have emerged as criti...

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Detaylı Bibliyografya
Yayımlandı:FASEB J
Asıl Yazarlar: Bernstock, Joshua D., Ye, Daniel, Smith, Jayden A., Lee, Yang-Ja, Gessler, Florian A., Yasgar, Adam, Kouznetsova, Jennifer, Jadhav, Ajit, Wang, Zhuoran, Pluchino, Stefano, Zheng, Wei, Simeonov, Anton, Hallenbeck, John M., Yang, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2018
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892725/
https://ncbi.nlm.nih.gov/pubmed/29146736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700711R
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