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DYRK1A and DYRK3 Promote Cell Survival through Phosphorylation and Activation of SIRT1
DYRK1A (the dual specificity tyrosine phosphorylation-regulated kinase 1A) plays an important role in body growth and brain physiology. Overexpression of this kinase has been associated with the development of Down syndrome in both human and animal models, whereas single copy loss-of-function of DYR...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857074/ https://ncbi.nlm.nih.gov/pubmed/20167603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102574 |
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