Phosphorylation and Inactivation of Glycogen Synthase Kinase 3β (GSK3β) by Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A (Dyrk1A)

Glycogen synthase kinase 3β (GSK3β) participates in many cellular processes, and its dysregulation has been implicated in a wide range of diseases such as obesity, type 2 diabetes, cancer, and Alzheimer disease. Inactivation of GSK3β by phosphorylation at specific residues is a primary mechanism by...

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Vydáno v:J Biol Chem
Hlavní autoři: Song, Woo-Joo, Song, Eun-Ah Christine, Jung, Min-Su, Choi, Sun-Hee, Baik, Hyung-Hwan, Jin, Byung Kwan, Kim, Jeong Hee, Chung, Sul-Hee
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303684/
https://ncbi.nlm.nih.gov/pubmed/25477508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.594952
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