Dyrk1A Phosphorylates p53 and Inhibits Proliferation of Embryonic Neuronal Cells

Down syndrome (DS) is associated with many neural defects, including reduced brain size and impaired neuronal proliferation, highly contributing to the mental retardation. Those typical characteristics of DS are closely associated with a specific gene group “Down syndrome critical region” (DSCR) on...

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Main Authors: Park, Joongkyu, Oh, Yohan, Yoo, Lang, Jung, Min-Su, Song, Woo-Joo, Lee, Sang-Hun, Seo, Hyemyung, Chung, Kwang Chul
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951261/
https://ncbi.nlm.nih.gov/pubmed/20696760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.147520
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