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Continued primer synthesis at stalled replication forks contributes to checkpoint activation
Stalled replication forks activate and are stabilized by the ATR (ataxia-telangiectasia mutated and Rad3 related)-mediated checkpoint, but ultimately, they must also recover from the arrest. Although primed single-stranded DNA (ssDNA) is sufficient for checkpoint activation, it is still unknown how...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Rockefeller University Press
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856894/ https://ncbi.nlm.nih.gov/pubmed/20385778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200909105 |
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