טוען...
MKK6 binds and regulates expression of Parkinson’s disease-related protein LRRK2
Mutations in leucine-rich repeat kinase 2 (LRRK2) are prevalent causes of late-onset Parkinson’s disease (PD). Here, we show that LRRK2 binds to mitogen-activated protein kinase (MAPK) kinases MKK3, 6, and 7, and that LRRK2 is able to phosphorylate MKK3, 6 and 7. Over-expression of LRRK2 and MKK6 in...
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| Main Authors: | , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856721/ https://ncbi.nlm.nih.gov/pubmed/20067578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06568.x |
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