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Investigating Convergent Actions of Genes Linked to Familial Parkinson's Disease
BACKGROUND: Mutations in LRRK2 are among the most frequent genetic changes identified in Parkinson's disease (PD), but how LRRK2 contributes to the pathophysiology of PD is not known. OBJECTIVES: To investigate how expressing wild-type or G2019S LRRK2 modifies cellular responses to rotenone, a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826451/ https://ncbi.nlm.nih.gov/pubmed/18322385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000113697 |
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