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Regulation of autophagy by LRRK2 in C. elegans
BACKGROUND: Mutations in LRRK2 are a common cause of familial Parkinson's disease. However, the mechanisms through which LRRK2 mutations contribute to neurodegeneration are poorly understood. OBJECTIVE: We investigated the effects of WT, G2019S, R1441C and kinase dead (KD) LRRK2 across multiple...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946265/ https://ncbi.nlm.nih.gov/pubmed/24192129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000355654 |
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