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Investigating Convergent Actions of Genes Linked to Familial Parkinson's Disease

BACKGROUND: Mutations in LRRK2 are among the most frequent genetic changes identified in Parkinson's disease (PD), but how LRRK2 contributes to the pathophysiology of PD is not known. OBJECTIVES: To investigate how expressing wild-type or G2019S LRRK2 modifies cellular responses to rotenone, a...

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Bibliografische gegevens
Hoofdauteurs: Wolozin, Benjamin, Saha, Shamol, Guillily, Maria, Ferree, Andrew, Riley, Misha
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: S. Karger AG 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826451/
https://ncbi.nlm.nih.gov/pubmed/18322385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000113697
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