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The role of glycophospatidylinositol anchor in the amplification of the scrapie isoform of prion protein in vitro

Transmissible spongiform encephalopathies are associated with an autocatalytic conversion of normal prion protein, PrP(C), to a protease-resistant form, PrPres. This autocatalytic reaction can be reproduced in vitro using a procedure called protein misfolding cyclic amplification (PMCA). Here we sho...

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Bibliografski detalji
Glavni autori: Kim, Jae-Il, Surewicz, Krystyna, Gambetti, Pierluigi, Surewicz, Witold K.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856614/
https://ncbi.nlm.nih.gov/pubmed/19854187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.10.049
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