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The role of glycophospatidylinositol anchor in the amplification of the scrapie isoform of prion protein in vitro
Transmissible spongiform encephalopathies are associated with an autocatalytic conversion of normal prion protein, PrP(C), to a protease-resistant form, PrPres. This autocatalytic reaction can be reproduced in vitro using a procedure called protein misfolding cyclic amplification (PMCA). Here we sho...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856614/ https://ncbi.nlm.nih.gov/pubmed/19854187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.10.049 |
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