Distinct Structures of Scrapie Prion Protein (PrP(Sc))-seeded Versus Spontaneous Recombinant Prion Protein Fibrils Revealed by Hydrogen/Deuterium Exchange

The detailed structures of prion disease-associated, partially protease-resistant forms of prion protein (e.g. PrP(Sc)) are largely unknown. PrP(Sc) appears to propagate itself by autocatalyzing the conformational conversion and oligomerization of normal prion protein (PrP(C)). One manifestation of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Smirnovas, Vytautas, Kim, Jae-Il, Lu, Xiaojun, Atarashi, Ryuichiro, Caughey, Byron, Surewicz, Witold K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782017/
https://ncbi.nlm.nih.gov/pubmed/19596861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.036558
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak