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Cholesterol Inhibits M-type K(+) Channels via Protein Kinase C-dependent Phosphorylation in Sympathetic Neurons
M-type (KCNQ) potassium channels play an important role in regulating the action potential firing in neurons. Here, we investigated the effect of cholesterol on M current in superior cervical ganglion (SCG) sympathetic neurons, using the patch clamp technique. M current was inhibited in a dose-depen...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856299/ https://ncbi.nlm.nih.gov/pubmed/20123983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.048868 |
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