Agonist-induced Localization of Gq-coupled Receptors and G Protein-gated Inwardly Rectifying K(+) (GIRK) Channels to Caveolae Determines Receptor Specificity of Phosphatidylinositol 4,5-Bisphosphate Signaling

G protein-gated inwardly rectifying K(+) (GIRK) channels are parasympathetic effectors in cardiac myocytes that act as points of integration of signals from diverse pathways. Neurotransmitters and hormones acting on the Gq protein regulate GIRK channels by phosphatidylinositol 4,5-bisphosphate (PIP(...

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Hlavní autoři: Cui, Shanyu, Ho, Won-Kyung, Kim, Seong-Tae, Cho, Hana
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009900/
https://ncbi.nlm.nih.gov/pubmed/21041306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.153312
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