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Cholesterol regulates HERG K(+) channel activation by increasing phospholipase C β1 expression
Human ether-a-go-go-related gene (HERG) K(+) channel underlies the rapidly activating delayed rectifier K(+) conductance (I(Kr)) during normal cardiac repolarization. Also, it may regulate excitability in many neuronal cells. Recently, we showed that enrichment of cell membrane with cholesterol inhi...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989356/ https://ncbi.nlm.nih.gov/pubmed/23793622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.25122 |
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