Cholesterol modulates ion channels via down-regulation of phosphatidylinositol 4,5-bisphosphate

Ubiquitously expressed Mg(2+)-inhibitory cation (MIC) channels are permeable to Ca(2+) and Mg(2+) and are essential for cell viability. When membrane cholesterol level was increased by pre-incubating cells with a water-soluble form of cholesterol, the endogenous MIC current in HEK293 cells was negat...

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Main Authors: Chun, Yoon Sun, Shin, Sora, Kim, Yonjung, Cho, Hana, Park, Myoung Kyu, Kim, Tae-Wan, Voronov, Sergey V., Paolo, Gilbert Di, Suh, Byung-Chang, Chung, Sungkwon
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891522/
https://ncbi.nlm.nih.gov/pubmed/20015154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06545.x
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