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Cholesterol modulates ion channels via down-regulation of phosphatidylinositol 4,5-bisphosphate
Ubiquitously expressed Mg(2+)-inhibitory cation (MIC) channels are permeable to Ca(2+) and Mg(2+) and are essential for cell viability. When membrane cholesterol level was increased by pre-incubating cells with a water-soluble form of cholesterol, the endogenous MIC current in HEK293 cells was negat...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891522/ https://ncbi.nlm.nih.gov/pubmed/20015154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06545.x |
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