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The Fibroblast Integrin α11β1 Is Induced in a Mechanosensitive Manner Involving Activin A and Regulates Myofibroblast Differentiation

Fibrotic tissue is characterized by an overabundance of myofibroblasts. Thus, understanding the factors that induce myofibroblast differentiation is paramount to preventing fibrotic healing. Previous studies have shown that mechanical stress derived from the integrin-mediated interaction between ext...

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מידע ביבליוגרפי
Main Authors: Carracedo, Sergio, Lu, Ning, Popova, Svetlana N., Jonsson, Roland, Eckes, Beate, Gullberg, Donald
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856250/
https://ncbi.nlm.nih.gov/pubmed/20129924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078766
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