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The Fibroblast Integrin α11β1 Is Induced in a Mechanosensitive Manner Involving Activin A and Regulates Myofibroblast Differentiation

Fibrotic tissue is characterized by an overabundance of myofibroblasts. Thus, understanding the factors that induce myofibroblast differentiation is paramount to preventing fibrotic healing. Previous studies have shown that mechanical stress derived from the integrin-mediated interaction between ext...

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Detalhes bibliográficos
Main Authors: Carracedo, Sergio, Lu, Ning, Popova, Svetlana N., Jonsson, Roland, Eckes, Beate, Gullberg, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856250/
https://ncbi.nlm.nih.gov/pubmed/20129924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078766
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